Yes there are a few types of Rattlesnakes in the South Carolina region. Copperhead (Agkistrodon contortrix) - Venomous
Cottonmouth/Water Moccasin (Agkistrodon piscivorus) - Venomous
Eastern Diamondback Rattlesnake (Crotalus adamanteus) - Venomous
Canebrake/Timber Rattlesnake (Crotalus horridus) - Venomous
Pigmy Rattlesnake (Sistrurus miliarius)-venomous
The above answer is basically correct, but although cottonmouths and copperheads are pit vipers like rattlesnakes, they are species in their own right, and not rattlesnakes.
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