How do you inactivate fetal bovine serum?

Fetal bovine serum (FBS) can be inactivated by heating it at 56°C for 30 minutes. This process denatures complement proteins and reduces the risk of contamination from pathogens. After inactivation, it is crucial to cool the serum quickly and store it at -20°C or -80°C for future use. Always handle FBS under sterile conditions to maintain its quality.