What is shine dalgarno sequenc?

The Shine-Dalgarno sequence is a ribosomal binding site in bacterial mRNA, crucial for the initiation of translation. It is a short, conserved nucleotide sequence located upstream of the start codon, typically rich in purines. This sequence pairs with a complementary region on the 16S rRNA of the small ribosomal subunit, facilitating the assembly of the ribosome on the mRNA. This interaction ensures that the ribosome is correctly positioned for protein synthesis.