Who made methotrexate?

Methotrexate was developed in the 1940s by Dr. Sidney Farber, an American physician and pathologist. He initially used it as a treatment for leukemia in children. Farber's work laid the foundation for the drug's use in cancer treatment and later for autoimmune diseases. Methotrexate is now widely used in various medical applications, including oncology and rheumatology.