Can you take hydrocodone Darvon and prochlorperazine together?

Prochlorperazine may enhance the hypotensive effect (abnormally low blood pressure) of Darvon and hydrocodone. The benefits of combined use of these medications usually outweigh the risks and you should talk to your doctor if you have any concerns as dosage and timing do play a role in unwanted side effects.

Also both Darvon and hydrocodone are central nervous system depressants and the use of these two drugs together should be monitored. Some side effects may include, but are not limited to, ataxia, confusion, drowsiness, respiratory depression, and weakness. Since both medications have the potential to depress CNS function it is important to recognize that the risk of unwanted effects may increase with such use.