Is it safe to take Tamiflu and penicillin at the same time?

The literature from the manufacturer of Tamiflu (oseltamivir) does not list that as a potential drug interaction problem. However, you should always notify your prescribing doctor if you are taking other medicines before you take any new prescriptions or use over the counter medicines with them.

The Tamiflu literature does state:


Information derived from pharmacology and pharmacokinetic studies of oseltamivir suggests that clinically significant drug interactions are unlikely.

No pharmacokinetic interactions have been observed when coadministering oseltamivir with amoxicillin, acetaminophen, cimetidine or with antacids (magnesium and aluminum hydroxides and calcium carbonates).