What is the difference between smallpox and yellow fever?

Smallpox and yellow fever are both viral diseases, but they differ significantly in their causative agents and transmission. Smallpox is caused by the variola virus and is characterized by fever and a distinctive rash, while yellow fever is caused by the yellow fever virus and primarily transmitted by mosquito bites, leading to fever, chills, and potentially severe liver damage. Additionally, smallpox has been eradicated through vaccination efforts, whereas yellow fever remains endemic in certain regions, necessitating ongoing vaccination and public health measures.