Are there spider in Ohio that when bitten cause the skin to break down?

The brown recluse is found there. Some staph infections also mimic a recluse spider bite as well.

ANS2:Yes, that is the mechanism of injury for all spider venom. Since they can't chew, they inject their prey with their proteolytic venom and the tissue turns into a 'bug smoothie' that they suck out. The Brown Recluse and the Black Widow Spiders are found in Ohio and their venoms are particularly good at liquefying human tissue.