Does pco2 decrease when bronchioles and systemic arterioles constrict?

Yes, pCO2 can decrease when bronchioles and systemic arterioles constrict. Bronchoconstriction reduces airflow and may limit CO2 exchange in the lungs, while systemic arteriolar constriction can decrease blood flow to tissues, leading to reduced CO2 production. However, the overall effect on pCO2 depends on the balance between ventilation and perfusion, as well as the metabolic activity of tissues. If ventilation is sufficiently impaired, pCO2 may actually increase despite systemic arteriolar constriction.