Where did the bird flu hit the hardest in the u.s.?

The bird flu, specifically the highly pathogenic avian influenza (HPAI), hit the hardest in the Midwest region of the United States, particularly affecting states like Iowa, Minnesota, and South Dakota. These areas experienced significant outbreaks in commercial poultry farms, leading to the culling of millions of birds to control the spread. The outbreaks had a substantial impact on the poultry industry, affecting both egg and meat production.