Is there any drug interaction between loratadine and Oxycontin?

There are no significant drug interactions between loratadine, an antihistamine, and Oxycontin (oxycodone), a strong opioid pain medication. However, both medications can cause drowsiness, so using them together may enhance this side effect. It's always best to consult with a healthcare provider or pharmacist before combining medications to ensure safety and proper management of any potential side effects.