How can I achieve the best results when cooking burgers in a cast iron skillet?

To achieve the best results when cooking burgers in a cast iron skillet, preheat the skillet on medium-high heat, season the burgers with salt and pepper, and cook them for about 4-5 minutes per side for medium-rare. Make sure not to overcrowd the skillet to allow for proper browning. Let the burgers rest for a few minutes before serving for juicier results.