How can you charge a large item on American express with a company that does not accept the card?

One way might be to establish a PayPal account and hope the company accepts PayPal. You can then use your American Express Card to pay PayPal.

The above method will work, but proceed with caution. As a merchant accepting credit cards with large ticketed items, the transaction will most likely be flagged as risky or suspicious and may result in some or all of the funds held by the processor (PayPal) for a duration of up to 6 mths.

When registered with a permanent Merchant Account ( with PayPal, Merchants processing over $3000.00 per month) you can avoid any funds held if the processor knows details of your business and have been advised of such large ticketed items in advanced). This goes to say with any processors providing Merchant Accounts. Abnormal large ticketed items are always flagged for the Merchant and the Consumer for the protection of all parties involved.