There is no cure for the common cold, which is caused by a coronavirus or rhinovirus. As this is a viral infection, antibiotics (which are only effective against bacteria) will not help and can cause other problems for your puppy.
The good news is, for the most part these viruses are self-limiting and your puppy will clear the virus within a week. Make sure your puppy is eating and drinking normally (if nursing, that he is still nursing well), that he is playing and exploring as normal and that he doesn't develop vomiting or diarrhea. If any of this doesn't happen, or your puppy doesn't start acting a lot better within 4 days, you need to take your puppy to a veterinarian for treatment. With severe infections, it is not uncommon for a puppy to not drink enough fluids and get dehydrated; your veterinarian can identify and treat this.
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