Is burkitt's disease caused by a change to the DNA?

Yes, Burkitt's lymphoma, often referred to as Burkitt's disease, is associated with genetic changes, particularly chromosomal translocations involving the MYC oncogene. These alterations lead to the uncontrolled proliferation of B-cells, contributing to the development of this aggressive form of non-Hodgkin lymphoma. The disease is frequently linked to Epstein-Barr virus (EBV) infection, which can also influence these genetic changes.