How does a person save themself if a 12 foot python is killing them?

If a person is being constricted by a large python, the primary focus should be on creating space to breathe and escape. They should try to protect their airway by using their hands to push against the snake's body and create a gap. If possible, they should aim to locate the snake's head and attempt to pry it away or strike it to distract it. Additionally, calling for help or using nearby objects to leverage against the snake can increase their chances of escape.