People have thought this combination:"sleeping medicine, anxiolytic (anti-anxiety medicine) and a narcotic/acetaminophen analgesic" is safe and they have never awakened from their drug induced slumber. Physicians are cautious when giving all of these medications ...even on a "take as needed" basis. A great deal depends on your tolerance level. There are many patients who have taken narcotics for a long time so they develop tolerance to the effects...same with the anxiety medicines. Heath Ledger was one such individual who sadly met with an early demise and deprived the world of his talents...but more importantly, his loved ones will live the rest of their days with holes in their hearts....as will all of his fans!
The most dangerous aspect of taking these three drugs is that they have "additive effects" and that means one drug boosts the effects of another. You may not be able to discern when you are reaching the critical "tipping" point. You won't be awake to judge the effects...you'll be unaware of anything...even your dreams!
If your doctor has prescribed the pain medicine during the day and the Ativan as needed with the understanding that the Ambien CR will be taken at night...then it is safe...the doctor knows the condition of your liver and kidneys and whether you are likely to become addicted to the individual drugs or the combination. As long as you do not deviate from the prescribed amounts/dosing schedules the combination is not necessarily lethal.
All three drugs are seriously affected by the slightest amount of alcohol...even in a person with a high alcohol tolerance.
The official answer is: avoid taking these together...make sure you follow your doctor's instructions and avoid all forms of alcohol and alcohol containing products (cold and cough syrups..) as well as muscle relaxants and antihistamines....this latter combination may cause permanent brain damage and possibly death with only ONE trial. If you are experimenting with this combination, please be aware that you do not know if your liver is healthy enough to metabolize the drugs and if your kidneys can effectively remove the metabolites.
Unless you have a serious injury, mega insomnia AND are nervous as a cat facing a Doberman, you don't need all three of these! Avoid them like the plague...
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