How do you defeat multiple man?

To defeat Multiple Man, you need to exploit his reliance on creating duplicates of himself. Target the original Jamie Madrox, as he is the source of the duplicates; if you can incapacitate him, the duplicates will fade away. Additionally, using strategies that disrupt his ability to create or control his copies—such as overwhelming force or tactics that isolate him—can also be effective in neutralizing the threat he poses.