To bleed the cooling system on a Mercedes-Benz S 500 after replacing the radiator and coolant, start by ensuring the heater is set to the maximum temperature and the fan is on low. Fill the coolant reservoir to the proper level, then start the engine and allow it to reach operating temperature while monitoring the coolant level. As the thermostat opens, air will escape, so periodically check and top off the coolant reservoir as necessary. Finally, once the engine cools, recheck the coolant level and add more if needed to ensure the system is fully bled.
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