How does oestrogen transport through the body?

Oestrogen is primarily transported in the bloodstream bound to carrier proteins, mainly sex hormone-binding globulin (SHBG) and albumin, which help stabilize the hormone and regulate its availability to tissues. A small fraction of oestrogen circulates in its free, unbound form, which is biologically active and able to enter target cells. Once inside the cells, oestrogen binds to specific receptors, triggering various physiological responses. The liver also plays a role in metabolizing and excreting oestrogen, ensuring its levels remain balanced in the body.