What was MC Escher's most famous art work?

M.C. Escher's most famous artwork is arguably "Relativity," created in 1953. This lithograph features a world with multiple gravitational pulls, where staircases and doorways lead to impossible spatial relationships, challenging viewers' perceptions of reality. Another iconic piece is "Drawing Hands," which depicts two hands drawing each other, blurring the lines between creator and creation. Both works exemplify Escher's mastery of perspective and his fascination with infinity and paradox.