How does tetanus toxin travel in neural tissue?

Tetanus toxin travels in neural tissue by retrograde axonal transport. After being internalized by peripheral neurons at the site of injury, the toxin is transported along the axon toward the cell body in the spinal cord. Once it reaches the central nervous system, it can diffuse to neighboring neurons, leading to the characteristic muscle spasms and rigidity associated with tetanus. This transport mechanism allows the toxin to spread efficiently within the nervous system.