The proamnion and area opaca are two distinct regions in the early development of the embryo. The proamnion is a thin layer of mesodermal tissue located at the anterior part of the embryo, contributing to the formation of the amniotic cavity. In contrast, the area opaca is the peripheral region of the blastodisc that remains more opaque due to the presence of denser yolk and cells, and it plays a role in supporting the embryo by providing nutrients. Essentially, the proamnion is involved in amniotic development, while the area opaca serves as a supportive structure.
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