Graded potentials can start as either depolarization or hyperpolarization, depending on the type of stimulus and the ion channels involved. Depolarization occurs when sodium channels open, allowing Na+ ions to flow into the cell, making the inside more positively charged. Conversely, hyperpolarization happens when potassium channels open, allowing K+ ions to exit, making the inside more negatively charged. Thus, graded potentials reflect changes in membrane potential that can vary in magnitude and direction.
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