Drinking alcohol after taking Antabuse (disulfiram) can lead to a severe reaction known as the disulfiram-alcohol reaction. This can cause symptoms such as flushing, nausea, vomiting, palpitations, and even respiratory distress. The reaction occurs because Antabuse inhibits the enzyme that breaks down acetaldehyde, a byproduct of alcohol metabolism, leading to a toxic buildup. It's crucial to avoid alcohol for at least 48 hours after taking Antabuse to prevent these adverse effects.
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