What is the Worth of a 1928 red seal Five Dollar Bill serial number I49073356A?

The serial number is just a counter and doesn't really help to ID a bill. What matters more is the series letter, if any, appearing next to the date.

With no letter, or any of A to E, your bill would be worth $6 if worn, up to $10 in better condition.

With an "F" series letter, the range would be $8 to $13