What neurotransmitter is involved with botulism?

Botulism is primarily associated with the neurotransmitter acetylcholine. The botulinum toxin produced by the bacterium Clostridium botulinum inhibits the release of acetylcholine at the neuromuscular junction, leading to muscle paralysis. This disruption in neurotransmission results in the characteristic symptoms of botulism, such as weakness and respiratory failure.