Is it safefor dogs to take vicodine?

Yes for LARGE enogh dogs that need it, but don't expect to get a prescription for it from your vet. I informed my vet that I had a some Vicodin and wanted to know if I could give my dog one of my pills when needed. My vet said "yes, it was okay". However, you should discuss with your vet, as it all depends on the breed/size, type of pain, and the dog's current life expectancy. Example: Vicodin will not work for inflamation, and could be toxic for little dogs. My dog is a 90 lb, 11 year old, golden retriever, who has transitional cell carcinoma which has spread. I only give her one maybe once or twice a week when she is having a really bad day. She does very well on them, often going from lethargic on the couch panting to wanting to play/cuddle/sometimes sleep. It would NOT be safe to give to a dog daily, or over a long period because of addiction/withdrawls/damage to liver (as is the case for humans). Nor would it be wise to give a human dosage to a very small animal, because of possible overdose. An alternative pain medication, more readily available, and recommended by vets for pain control in dogs is TRAMADOL. Talk to a vet about getting the right dosage based on your pet's weight. Good luck to you! Note: I am not a vet, and so this information is only based on my dog's experience. You are best to just ask your vet if it's okay for your dog.