What antibiotic is best for reaction to bee stings or holly berry bush stabs?

Antibiotics are of no value in treating either of these conditions. Antibiotics are chemical agents that act against the growth of bacteria in the body, either by killing them outright (bactericidal) or by weakening them so that they cannot reproduce efficiently (bacteriOStatic). They act by disrupting the biochemistry of the bacteria. They are either naturally occurring (as in penicillin) or semisynthetic derivatives. Use of antibiotics for anything other than a bacterial infection (like bee stings or thorn punctures) is dangerous for at least two reasons. First, indiscriminate use has resulted in the development of antibiotic-resistant strains of some very virulent (deadly) bacteria. Second, some individuals are very allergic to some antibiotics, and exposure to the antibiotic can be life-threatening.