How many offspring do mice have?

Responsibly? MIce can be bred around 3 times and must have breaks in between matings. A pair of mice can make up to 20 (but more commonly somewhere around 10) babies but the babies must wait until they are around 3 months old to breed, or the chances of complications rise. So, if you are a responsible breeder, a pair of mice could make somewhere around 50-100 mice.

Even if you are breeding mice for reptile food, you should still do research and follow these guidelines. Just dumping mice into a tub to breed and breed and breed in unsanitary conditions is unethical treatment of animals... not only that, but what goes into your mouse, goes into your snake. If you breed without considering the health of the animal and your pet eats that animal, it is not getting optimum nutrition.