Hormone secretion from the ovaries, primarily estrogen and progesterone, plays a crucial role in regulating the endometrium. Estrogen stimulates the proliferation and thickening of the endometrial lining during the follicular phase, preparing it for potential implantation. Following ovulation, progesterone further transforms the endometrium into a secretory phase, promoting glandular development and increasing blood supply to support a potential pregnancy. If fertilization does not occur, the withdrawal of these hormones leads to the breakdown of the endometrium, resulting in menstruation.
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