A 6-pound tri-tip will typically take about 4 to 6 hours to cook at 250°F. The exact time can vary based on factors like the thickness of the meat and whether it’s being cooked with a direct or indirect heat method. It's best to use a meat thermometer to check for doneness, aiming for an internal temperature of 135°F for medium-rare. Let it rest for 15-20 minutes before slicing to allow the juices to redistribute.
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