Which provision empowers the president to appoint a new vice president if a vacancy exist in that office?

The 25th Amendment to the United States Constitution empowers the president to appoint a new vice president in the event of a vacancy in that office. Specifically, Section 2 of the Amendment states that the president shall nominate a vice president who takes office upon confirmation by a majority vote of both Houses of Congress. This provision was ratified in 1967 to provide a clear process for filling vice presidential vacancies.