How do you replace fuel pump on 2000 E250 ford van?

To replace the fuel pump on a 2000 Ford E250 van, first, relieve the fuel system pressure by removing the fuel pump relay and starting the engine until it stalls. Next, disconnect the battery and drain the fuel tank. Remove the tank by unscrewing the straps and disconnecting the fuel lines and electrical connectors. Finally, remove the old fuel pump from the sending unit, install the new pump, and reassemble the tank and connections before reattaching the battery and testing the system.