A Punnett square for congenital hypothyroidism, which is often inherited in an autosomal recessive manner, typically involves two parents who are carriers of the recessive allele (represented as "Hh"). In the Punnett square, the possible genotypes for their offspring would be HH (normal), Hh (carrier), and hh (affected). The ratiOS would be 1 HH : 2 Hh : 1 hh, indicating a 25% chance for a child to be affected by congenital hypothyroidism if both parents are carriers.
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