What cells express IFN-a?

Interferon-alpha (IFN-α) is primarily produced by plasmacytoid dendritic cells (pDCs) in response to viral infections. Other cells, such as macrophages and certain types of lymphocytes, can also produce IFN-α, particularly in response to specific stimuli like cytokines or viral components. These cells play a crucial role in the immune response by enhancing antiviral activity and modulating the immune system.