Would a timing belt failure result in a damaged engine on a 2000 Honda odyssey?

A 2000 Honday Odyssey is an interference engine. This means that that if the piston and the valves are not in proper timing (for example when the timing belt breaks) there is a possibility that the pistons will hit the valves and cause damage because they have the potential to occupy the same space at the same time (i.e. INTERFER with each other). On these types of engines since engine damage is very likely in the event of timing belt failure, it is HIGHLY recommended that they be changed at the recommended interval.