What is Campbell model of lambda phage?

The Campbell model of lambda phage describes the genetic recombination that occurs during the lysogenic cycle of the bacteriophage lambda. In this model, the phage DNA integrates into the host bacterium's chromosome through homologous recombination, allowing the viral DNA to be replicated along with the host's DNA during cell division. This integration process is critical for the establishment of the lysogenic state, where the viral genome remains dormant until triggered to enter the lytic cycle. The model emphasizes the role of specific sequences and enzymes in facilitating this integration.