Septra, a combination of sulfamethoxazole and trimethoprim, is primarily used as an antibiotic. While it is not known to directly trigger herpes outbreaks, any medication that affects the immune system or alters the body's balance could potentially influence the frequency of outbreaks in individuals with herpes. If someone experiences increased outbreaks while taking Septra, they should consult their healthcare provider for further evaluation and management.
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