How many years has animal testing been used?

I'm not sure of the exact date but I think it was 15th/16th century.

The first animal test was done by an Italian scientist to find out if dancing the tarantella would cure a tarantula bite (as was believed by them and their ancestors, because they thought that was what animals did).

He took a rabbit and made a tarantula bite it, he played it music but the rabbit did not dance; it was of course nonsense.