What does granuloma mean?

A granuloma is a small, localized inflammation or mass of tissue that forms in response to chronic infection, irritation, or foreign substances. It consists of a collection of immune cells, primarily macrophages, that attempt to isolate and contain the offending agent. Granulomas are commonly associated with conditions like tuberculosis, sarcoidosis, and certain autoimmune diseases. They can be detected through imaging or biopsy and may require treatment depending on the underlying cause.