Can you clip your iguanas nails?

Presumably you're talking about a 'pet' hedgehog... Unless you're REALLY confident you can do it without harming the animal - the best solution would be to let a vet do it ! You can easily injure a struggling animal if you're not confident enough to do it. The easiest way to keep its nails in check - would be to provide some large pieces of slate in its enclosure. Slate is abrasive, and will file the animals nails as it walks.