Do you lose weight on methamphetamine?

No doubt, and you'll start to exhibit psychotic behaviors, become addicted possibly become physically ill and possibly even die from it. Diet and exercise are still the best way to loose weight, but if you're asking this question you've probably already made up your mind and have somehow convinced yourself that "it won't happen to me." Let me warn you right now: It WILL happen to you. If you turn to amphetamines to loose weight you WILL have serious problems. Even under a doctors supervision, amphetamines are dangerous and can result in some serious problems.