Keflex, or cephalexin, can cause heartburn as a side effect due to its potential to irritate the gastrointestinal tract. It may disrupt the natural balance of gut bacteria, leading to digestive disturbances. Additionally, some individuals may experience increased acid production or relaxation of the lower esophageal sphincter, contributing to heartburn symptoms. If heartburn persists, it's advisable to consult a healthcare provider.
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