Treacher Collins syndrome is primarily caused by mutations in the TCOF1 gene, which can be inherited in an autosomal dominant manner. This means that an affected individual has a 50% chance of passing the mutated gene to each of their children. In some cases, the syndrome can also result from new mutations that occur spontaneously, meaning it may not always be inherited from a parent. If a child inherits the mutated gene, they may exhibit varying degrees of the syndrome's characteristic features.
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