Very unlikely. You may be thinking of the fact that there were two different designs issued under the same 2006 series. The Federal Reserve originally planned to keep issuing the old green-and-black design, but changed its plans and decided to add anti-counterfeiting features. The old bills continued to be printed while the new purple-and-black design was prepared, so both designs were issued under the same series.
Neither design is rare, and both are only worth $5 despite a lot of internet rumors.
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