Frontline, Revolution and Advantage can all be safely used on cats and dogs interchangeably, as the ingredients are identical, you just need to know the correct doses.
Frontline Plus for Dogs contains (fipronil 9.8% and S-methoprene 8.8%)
whereas
Frontline Plus for Cats contains (fipronil 9.8% and S-methoprene 11.8%)
Dogs are given a dose of 0.067ml of Frontline solution per kilogram of bodyweight.
So a 10.0kg dogs need a dose of 0.67ml
an 6.0kg dog only really needs 0.40ml
ALL cats are given a set dose of 0.50ml
The Frontline Plus for cats formula contains exactly the same concentration of Fipronil (the main ingredient which kills fleas, ticks, and lice) as the Frontline Plus for dogs formula.
The only difference is the cat version contains 3% MORE of the ingredient methoprene than the dog formula.
Giving your dog a tiny 3% more methoprene will not harm it. Look up the toxixity of methoprene online for yourself and see.
Methoprene simply acts as a juvenile hormone analogue in fleas, it keeps the fleas "young". The flea larvae are prevented from completing the metamorphosis into adults and subsequently die.
Note: Not all dog and cat medications are interchangeable. You could poison your pet if you don't do your research first.
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