How many casualties in the huaynaputina erruption of 1600?

The Huaynaputina eruption of 1600 in present-day Peru is estimated to have caused significant casualties, with death toll estimates ranging from 1,500 to 6,000 people. The eruption not only led to immediate fatalities due to volcanic activity but also resulted in widespread famine and disease in the following years, impacting local populations. The eruption is considered one of the largest in South American history and had serious environmental and socio-economic consequences.