What Reduced brain levels of the neurotransmitter are involved in the progressive memory loss that characterizes Alzheimer's?

Reduced brain levels of the neurotransmitter acetylcholine are involved in the progressive memory loss characteristic of Alzheimer's disease. Acetylcholine is crucial for learning and memory, and its depletion is linked to the cognitive decline observed in Alzheimer's patients. This reduction results from the degeneration of cholinergic neurons, which further exacerbates memory impairment and other cognitive deficits associated with the disease.