How do you remove a downloader Trojan virus in a 322dm3d.dll system file?

The dll file could actually be the cause of you getting the downloader virus. First focus on deleting the dll file and then you can run a virus program to eliminate any other viruses on your computer. First find out what processes that dll file has attached itself to. Go to run and enter procexp. When that pops up go to find dll or handle and enter your dll file name. It will specify which processes it has attached itself. If it's not a vital process then you can kill the process and subsequently delete that dll file. If it's attached to the winlogon.exe or explorer processes then here are a few more steps. Right click on each process seperately and go to properties. Under threads you will need to right click and kill each instance of the dll. You will also need to do this with any handles listed. I had to suspend the winlogon handle. Then you should be able to delete that dll. If it's protected and you can't delete it. Move the file to another folder... I moved it to a new folder in My Documents. Then reboot and you should be able to delete that file. Good luck...